Atlanta World Map Crafting Dead
Atlanta World Map Crafting Dead
This website is not affiliated with the author in any way. All content posted on this site is protected under copyright laws, but is is used for discussion purposes. Do not reproduce any of this material without permission, unless exendv [at] hotmail [dot] com. If you have a good idea, shoot me a message!Association of IL-17A -197 T/G gene polymorphism with susceptibility of Turkish patients with essential hypertension.
Interleukin (IL)-17 cytokine family includes IL-17A, IL-17B, IL-17C, and IL-17E and belongs to the family of IL-17 cytokines. IL-17 cytokines have been proposed to play a role in the pathogenesis of systemic inflammatory diseases, infectious diseases, and hypertension. This study investigated the distribution of IL-17A -197 T/G gene polymorphism and the association of IL-17 gene polymorphism with essential hypertension (EH) in Turkish population. PCR-RFLP method was used to determine the genotypes of IL-17A -197 T/G polymorphism in the genomic DNA from the patients with EH and the controls. Statistical analyses were performed using SPSS 11.5 software. There was a significant difference in the distribution of IL-17A -197 T/G genotypes and alleles between the patients and the controls (p = 0.0019, p = 0.0013, respectively). The distribution of the IL-17A -197 T/G genotypes in patients with high-normal blood pressure (BP), stage I EH, stage II EH, and stage III-IV EH was significantly different (p = 0.0019, p = 0.0021, p = 0.0015, p = 0.0146). There was a significant difference in the distributions of haplotypes among patients and controls (p = 0.0338). The haplotype GCC was observed at a significantly increased frequency in the patients compared with the controls (p = 0.0022, OR = 3.4 [1.5-7.7]). Our results showed that the IL-17A -197 T/G gene polymorphism was associated with susceptibility of Turkish patients with EH.Nairn railway station
Nairn railway station was an intermediate station between Inverness and Perth railway stations in the parish of Gairloch, in the Scottish Highlands.
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