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Forum. JRiver Media Center v25.0.24 Fix, Logix Free MP3 Converter 3.3.1 License. Find out how to download and install JRiver Media Center For more, including instructions,.Tumor suppressor mutation on chromosome 12q in relation to epithelial ovarian cancer.
Inactivation of tumor suppressor gene(s) on chromosome 12q may play a role in the pathogenesis of epithelial ovarian cancer. We therefore analyzed a panel of five tumors from patients with sporadic epithelial ovarian cancer for loss of heterozygosity on chromosome 12q. Five microsatellite markers were tested and an intragenic marker, D12S40, was found to be monosomic in two of the five tumors (40%), indicating loss of the wild-type allele. Loss of heterozygosity was thus demonstrated in two of the five tumors (40%). Allelic loss on chromosome 12q in ovarian cancer suggests the existence of a tumor suppressor gene in this region and may be of importance for better understanding of the pathogenesis of epithelial ovarian cancer.![](envhper00444-0169.tif “scanned-page”){.177}

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” FILE: keyword.vim
” AUTHOR: Aaron Kesler
” COPYRIGHT: Copyright (C) 2014, 2015


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